Although United are not in action this week, the resumption of hostilities across Europe marks the emergence from the depths of winter.
And for Scholes, it is also the start of a run-in to what he hopes will be a glorious end to the season.
"It's the sign for the run-in," said the veteran midfielder. "It just kind of happens without you knowing it. You know there are 12 games left in the league, the FA Cup is getting down to the latter stages and Europe is starting again.
"Every game becomes more important. It is the time to stand up and start playing."
TOUGH PLACE
United could not have made a better start, securing a derby-day victory over Manchester City at Old Trafford.
That result - and Chelsea's failure to overcome Fulham at Craven Cottage on Monday - have arguably turned the title race into a straight fight between United and Arsenal.
Scholes, though, only has eyes for non-league Crawley in the FA Cup, and then Didier Deschamps' Marseille, who stand between United and a place in the quarter-finals, where they lost in agonising fashion to Bayern Munich last season.
"Marseille won't be easy," he said. "It's a tough place. We played there before quite a few years ago and got beaten.
"But we are looking forward to it. Hopefully it is the start of a good end to the season for us and we can go all the way to the final again and win it."